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Treatment - medication
As recently as a decade ago, treatments available were limited to the use of astringent instillations, such as chlorpactin (oxychlorosene) or silver nitrate, designed to kill "infection" and/or strip off the bladder lining. In 2005, our understanding of IC/PBS has improved dramatically and these therapies are now no longer done. Rather, IC/PBS therapy is typically multi-modal, including the use of a bladder coating, an antihistamine to help control mast cell activity and a low dose antidepressant to fight neurogenic inflammation.
Other articles from the section: Interstitial cystitis
Nomenclature
Originally called interstitial cystitis, the name for this disorder changed to interstitial cystitis/painful bladder syndrome in the period 2002-2005. In 2007, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) began using the umbrella term Urologic Chronic Pelvic Pain Syndromes (UCPPS) to refer to pain syndromes associated with the bladder (i.e. interstitial cystitis/painful bladder syndrome, IC/PBS) and the prostate gland (i.e. chronic prostatitis/chronic pelvic pain syndrome, CP/CPPS). In ...Section: Interstitial cystitis
Treatment - pain control
Pain control is usually necessary in the IC/PBS treatment plan. The pain of IC/PBS has been rated equivalent to cancer pain and may lead to central sensitization if untreated. Medication. The use of a variety of traditional pain medications, including opiates and synthetic opioids like tramadol, is often necessary to treat the varying degrees of pain. Even children with ...Section: Interstitial cystitis
Treatment - medication (bladder coatings)
Other bladder coating therapies include Cystistat (sodium hyaluronate) and Uracyst (chondroitin). They are believed to replace the deficient GAG layer on the bladder wall. Like most other intravesical bladder treatments, this treatment may require the patient to lie for 20 - 40 minutes, turning over every ten minutes, to allow the chemical to 'soak in' and give a good coating, before it is passed out with the ...Section: Interstitial cystitis