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Treatment - medication
As recently as a decade ago, treatments available were limited to the use of astringent instillations, such as chlorpactin (oxychlorosene) or silver nitrate, designed to kill "infection" and/or strip off the bladder lining. In 2005, our understanding of IC/PBS has improved dramatically and these therapies are now no longer done. Rather, IC/PBS therapy is typically multi-modal, including the use of a bladder coating, an antihistamine to help control mast cell activity and a low dose antidepressant to fight neurogenic inflammation.
Other articles from the section: Interstitial cystitis
About interstitial cystitis/painful bladder syndrome
Interstitial cystitis/painful bladder syndrome (commonly abbreviated to "IC/PBS"), is a urinary bladder disease of unknown cause characterised by pain associated with urination (dysuria), urinary frequency (as often as every 10 minutes), urgency, and pressure in the bladder and/or pelvis. Pain that worsened with a certain food or ...Section: Interstitial cystitis
Symptoms
The symptoms of IC/PBS are often misdiagnosed as a "common" bladder infection (cystitis) or a UTI. However IC/PBS has not been shown to be caused by a bacterial infection, and the mis-prescribed treatment of antibiotics is ineffective. The symptoms of IC/PBS may also initially be attributed to prostatitis and epididymitis (in men) and endometriosis and uterine fibroids (in women). The most common symptom of IC/PBS is pain, which is found in 100% of patients, frequency (82% of patients) and nocturia (62%). In general, symptoms ...Section: Interstitial cystitis
Treatment - diet
The foundation of therapy is a modification of diet to help patients avoid those foods which can further irritate the damaged bladder wall. Common offenders are highly spiced or acidic foods and include alcohol, coffees, teas, herbal teas, green teas, all sodas (particularly diet), concentrated fruit juices, tomatoes, citrus fruit, cranberries, the B vitamins, vitamin C, monosodium glutamate, chocolate, and potassium-rich foods such as bananas. Most IC/PBS support groups and many urology clinics have diet ...Section: Interstitial cystitis