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Section: Interstitial cystitis (list 1)

About interstitial cystitis/painful bladder syndrome

  Interstitial cystitis/painful bladder syndrome (commonly abbreviated to "IC/PBS"), is a urinary bladder disease of unknown cause characterised by pain associated with urination (dysuria), urinary frequency (as often as every 10 minutes), urgency, and pressure in the bladder and/or ...

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Section: Interstitial cystitis

  1. > Treatment - medication (Amitriptyline)
  2. > Treatment - pelvic floor treatments
  3. > Treatment - medication (pentosan polysulfate)
  4. > About interstitial cystitis/painful bladder syndrome
  5. > Diagnosis

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Other articles from the section: Interstitial cystitis

Causes

  The cause of IC/PBS is unknown, though several theories have been put forward (these include autoimmune, neurologic, allergic and genetic). Regardless of the origin, it is clear that the majority of IC/PBS patients struggle with a damaged urothelium, or bladder lining. When the surface glycosaminoglycan (GAG) layer is damaged (via a urinary tract infection (UTI), excessive consumption of coffee or sodas, traumatic injury, etc.), urinary chemicals can "leak" into surrounding tissues, causing pain, inflammation, and urinary symptoms. Oral ...

Section: Interstitial cystitis

Treatment - bladder distension

  Bladder distension (a procedure which stretches the bladder capacity, done under general anaesthesia) has shown some success in reducing urinary frequency and giving pain relief to patients. However, many experts still cannot understand precisely how this can cause pain relief. Recent studies showing that pressure on pelvic trigger points can relieve symptoms may be connected. ...

Section: Interstitial cystitis

Treatment - medication (bladder coatings)

  Other bladder coating therapies include Cystistat (sodium hyaluronate) and Uracyst (chondroitin). They are believed to replace the deficient GAG layer on the bladder wall. Like most other intravesical bladder treatments, this treatment may require the patient to lie for 20 - 40 minutes, turning over every ten minutes, to allow the ...

Section: Interstitial cystitis

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