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Section: Interstitial cystitis (list 3)
Treatment - medication (Amitriptyline)
Amitriptyline can reduce symptoms in patients with IC/PBS. Patient overall satisfaction with the therapeutic result of amitriptyline was excellent or good in 46%.Section: Interstitial cystitis
Other articles from the section: Interstitial cystitis
Treatment - pelvic floor treatments
Work by Wise and Anderson (see details) has shown that urologic pelvic pain syndromes, such as IC/PBS and CP/CPPS, may have no initial trigger other than anxiety, often with an element of Obsessive Compulsive Disorder or other anxiety-spectrum problem. This is theorized to leave the pelvic area in a sensitized condition resulting in a loop of muscle tension and heightened neurological feedback (neural wind-up). ...Section: Interstitial cystitis
Causes
The cause of IC/PBS is unknown, though several theories have been put forward (these include autoimmune, neurologic, allergic and genetic). Regardless of the origin, it is clear that the majority of IC/PBS patients struggle with a damaged urothelium, or bladder lining. When the surface glycosaminoglycan (GAG) layer is damaged (via a urinary tract infection (UTI), excessive consumption of coffee or ...Section: Interstitial cystitis
Treatment - medication (bladder coatings)
Other bladder coating therapies include Cystistat (sodium hyaluronate) and Uracyst (chondroitin). They are believed to replace the deficient GAG layer on the bladder wall. Like most other intravesical bladder treatments, this treatment may require the patient to lie for 20 - 40 minutes, turning over every ten minutes, to allow the chemical to 'soak in' and give a good coating, before it is passed out with the ...Section: Interstitial cystitis