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Section: Interstitial cystitis (list 1)

Symptoms

  The symptoms of IC/PBS are often misdiagnosed as a "common" bladder infection (cystitis) or a UTI. However IC/PBS has not been shown to be caused by a bacterial infection, and the mis-prescribed treatment of antibiotics is ineffective. The symptoms of IC/PBS may also initially be attributed to ...

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Section: Interstitial cystitis

  1. > Treatment - medication (Amitriptyline)
  2. > Treatment - pelvic floor treatments
  3. > Treatment - medication (pentosan polysulfate)
  4. > About interstitial cystitis/painful bladder syndrome
  5. > Diagnosis

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Other articles from the section: Interstitial cystitis

Causes

  The cause of IC/PBS is unknown, though several theories have been put forward (these include autoimmune, neurologic, allergic and genetic). Regardless of the origin, it is clear that the majority of IC/PBS patients struggle with a damaged urothelium, or bladder lining. When the surface glycosaminoglycan (GAG) layer is damaged (via a urinary tract infection (UTI), excessive ...

Section: Interstitial cystitis

Treatment - medication (bladder instillations)

  DMSO, a wood pulp extract, is the only approved bladder instillation for IC/PBS yet it is much less frequently used in urology clinics. Research studies presented at recent conferences of the American Urological Association by C. Subah Packer have demonstrated that the FDA approved dosage of a 50% solution of DMSO had the potential of creating irreversible muscle contraction. However, a lesser solution of 25% was found to be reversible. Long term use is questionable, at best, ...

Section: Interstitial cystitis

Treatment - pain control

  Pain control is usually necessary in the IC/PBS treatment plan. The pain of IC/PBS has been rated equivalent to cancer pain and may lead to central sensitization if untreated.  Medication. The use of a variety of traditional pain medications, including opiates and synthetic opioids like tramadol, is often necessary to treat the varying degrees of pain. Even children with IC/PBS should be appropriately addressed regarding pelvic pain, and receive necessary treatment to manage ...

Section: Interstitial cystitis

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