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Section: Interstitial cystitis (list 1)

Diagnosis

  Diagnosis has been greatly simplified in recent years with the development of two new methodologies. The Pelvic Pain Urgency/Frequency (PUF) Patient Survey, created by C. Lowell Parsons, is a short questionnaire that will help doctors identify if pelvic pain could be coming from the bladder. The KCl ...

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Section: Interstitial cystitis

  1. > Treatment - medication (Amitriptyline)
  2. > Treatment - pelvic floor treatments
  3. > Treatment - medication (pentosan polysulfate)
  4. > About interstitial cystitis/painful bladder syndrome
  5. > Diagnosis

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Other articles from the section: Interstitial cystitis

Causes

  The cause of IC/PBS is unknown, though several theories have been put forward (these include autoimmune, neurologic, allergic and genetic). Regardless of the origin, it is clear that the majority of IC/PBS patients struggle with a damaged urothelium, or bladder lining. When the surface glycosaminoglycan (GAG) layer is damaged (via a urinary tract infection (UTI), excessive consumption of coffee or sodas, traumatic injury, etc.), urinary chemicals can "leak" into surrounding tissues, causing pain, inflammation, and urinary symptoms. Oral medications like Elmiron and ...

Section: Interstitial cystitis

Treatment - medication (bladder instillations)

  DMSO, a wood pulp extract, is the only approved bladder instillation for IC/PBS yet it is much less frequently used in urology clinics. Research studies presented at recent conferences of the American Urological Association by C. Subah Packer have demonstrated that the FDA approved dosage of a 50% solution of DMSO ...

Section: Interstitial cystitis

Treatment - pain control

  Pain control is usually necessary in the IC/PBS treatment plan. The pain of IC/PBS has been rated equivalent to cancer pain and may lead to central sensitization if untreated.  Medication. The use of a variety of traditional pain medications, including opiates and synthetic opioids like ...

Section: Interstitial cystitis

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