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Section: Erectile Dysfunction (list 1)
Pathophysiology
Penile erection is managed by two different mechanisms. The first one is the reflex erection, which is achieved by directly touching the penile shaft. The second is the psychogenic erection, which is achieved by erotic or emotional stimuli. The former uses the peripheral nerves and the lower parts of the spinal cord, whereas the latter uses the limbic system of the brain. In both conditions, an intact neural system is required for a successful and ...Section: Erectile Dysfunction
Other articles from the section: Erectile Dysfunction
Alprostadil
Alprostadil can be injected into the penis or inserted using a special applicator - usually just before sexual intercourse. Alprostadil has also become available in some countries as a topical cream (under the brand name Befar), and preliminary studies have shown a clinical efficacy of up to 83%. It has an onset of action of 10-15 minutes and its effects can last over 4 ...Section: Erectile Dysfunction
History
The earliest attempts at treating erectile dysfunction date back to Muslim physicians and pharmacists in the medieval Islamic world. They were the first to prescribe medication for the treatment of this problem, and they developed several methods of therapy for this issue, including a single-drug therapy method where a drug was prescribed and a "combination method of either a drug ...Section: Erectile Dysfunction
Causes
Drugs (Anti-depressants (SSRIs) and Nicotine are most common. A study entitled "Drug-induced mal sexual dysfunction" concluded that of the 12 most commonly prescribed medications on the market today, 8 of those medications list "impotence" as a side-effect of the drug. Other drugs such as alcohol, cocaine, and heroin negatively impact male sexual libido.) Neurogenic Disorders (spinal cord and brain injuries, nerve disorders such as Parkinson's disease, Alzheimer's disease, multiple sclerosis, and stroke.) Arterial ...Section: Erectile Dysfunction