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News: December 2, 2009

Fatty acids in diet affect ulcerative colitis risk

December 2, 2009

People who eat lots of red meat, cook with certain types of oil, and use some kinds of polyunsaturated fatty acid (PUFA)-heavy margarines may be increasing their risk of a painful inflammatory bowel disease, a study in more than 200,000 Europeans shows.
These foods are high in linoleic acid and the study have found that people who were the heaviest consumers of this omega-6 PUFA were more than twice as likely to develop ulcerative colitis as those who consumed the least.
Dr. Andrew Hart of the University of East Anglia in Norwich, UK, and his colleagues also found that eating more eicosapentaenoic acid, an omega-3 fatty acid found in fish and fish oils, was associated with a lower risk of the disease.
While people need a certain amount of linoleic acid to survive, Hart noted in an interview with Reuters Health, excess amounts are taken up into the lining of the colon, and if they're released, they can promote inflammation. Omega-3 fatty acid, he added, does the opposite. "It basically dampens down inflammation," he explained.
To investigate the role of fatty acids and ulcerative colitis, a life-long disease characterized by inflammation of the lining of the large intestine, Hart and his colleagues looked at data from the European Prospective Investigation into Cancer and Nutrition (EPIC) trial, which includes over half a million people from 10 European countries.
Their analysis included 203,193 men and women 30 to 74 years old. During follow-up, which ranged from about 2 to 11 years, 126 people developed ulcerative colitis.
People in the top quartile of linoleic acid intake (they were consuming around 13 to 38 grams a day) were 2.5 times more likely to have developed the disease than people who consumed the least, about 2 to 8 grams daily.
There's currently no proven dietary treatment for ulcerative colitis, Hart noted, but the current findings raise the possibility that eating a diet low in linoleic acid could be helpful.
While a Western-style, red-meat-heavy diet is high in this fatty acid and low in omega-3s, Hart noted, a more Mediterranean style eating pattern -- with plenty of fruits and vegetables, fish, and nut oils -- would be low in linoleic acid and high in omega-3.
He estimated that if omega-3s do help prevent ulcerative colitis, eating a couple of servings of fish a week would probably be protective.


Archive issues: (50)

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December 5, 2009 | Half of teen girls have STIs by 2 years of first sex

Within 2 years of having sex for the first time, half of teenage girls may be at least one of three common sexually transmitted infections (STIs), according to results of a study published today. Often, those girls are infected by the age of 15.  Researchers followed 386 urban adolescent girls aged 14 to 17 for up to 8 years. Within 2 years of becoming sexually active, half of the girls were infected with at ...

December 4, 2009 | Antidepressants May Change Your Personality

Taking antidepressants may not only help alleviate depression, but could make you more extraverted and less neurotic, new research suggests.  Extraversion, which is associated with positive emotions, is believed to help protect from depression, while neuroticism, the tendency to experience negative emotions and emotional instability, is thought to contribute to depression.   Becoming more ...

December 3, 2009 | Smoking Exposure Now Linked to Colon, Breast Cancers

Add colorectal cancer to the list of malignancies caused by smoking, with a new study strengthening the link between the two.  And other studies are providing more bad news for people who haven't ...

Archive list: 1 2 3 [4] 5 6 7 8 9 10 11 12 13 14 15 16 17

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