Sections

Alphabetical list:

A B C D E F G H I J K L M N O P R S T U V W X Y Q Z 1 2 3 4 5 6 7 8 9

News: November 23, 2009

Genetic Variant Slows AIDS Progression

November 23, 2009

Scientists report that a genetic variation appears to play a major role in slowing disease progression in HIV-infected patients.
In fact, those with the variation appear to take years longer to develop AIDS and die of complications of the disease.
"We're honing in on factors that vary across individuals that make a person more or less susceptible to HIV, in terms of how rapidly someone develops the disease," said study co-author Mary Carrington, a senior principal investigator at the U.S. National Cancer Institute.
However, this new knowledge won't translate into immediate benefits for patients with HIV.
AIDS remains a major killer in many parts of the world, but HIV - the virus that causes it - doesn't affect infected people the same way. "People progress to AIDS at hugely different rates," Carrington explained. "Some people progress within a year, while some have been infected for 20 years and still control the virus and don't have the disease."
It appears that three factors affect how the disease strikes a person, she said. One is the environment: the world in which a person lives. Another is the patient's genetic makeup. And the third is the genetic makeup of the virus itself.
In the study, published in the Nov. 22 online edition of Nature Genetics, Carrington and colleagues looked at genetic and medical records for hundreds of HIV-infected men. They were trying to see if genetic variations affected how the men fared.
The researchers found that a variation linked to higher levels of a protein known as HLA-C boosted the men's ability to avoid progressing to AIDS. It appeared to delay both the progression to AIDS and to death by years, Carrington said.
The genetic variation makes it easier for the immune system to kill cells that have been infected with the virus, she said. It does this by allowing immune cells to gain greater access to the infected cells, she explained.
Carrington said this genetic variation isn't related to another gene-related trait that makes some people virtually immune to HIV.
The study "hints at ways we might ultimately develop a vaccine or immune-based therapies that could modify or maybe even prevent the development of HIV disease," said Rowena Johnston, vice president of research with the Foundation for AIDS Research in New York City.
"The finding that a single piece of DNA can be strongly associated with something as complex as the control of HIV soon after infection is especially intriguing, not least because we know that early control of infection sets the stage for the entire course of the disease," Johnston noted.
What's next? The ultimate goal, Carrington said, is "to have a complete list of every genetic variance that is affecting how rapidly the disease develops."
That, in turn, could help physicians figure out how to better treat patients.


Archive issues: (50)

Archive list: 1 2 3 4 5 6 7 8 [9] 10 11 12 13 14 15 16 17

November 20, 2009 | Yes, Cats Can Catch the Swine Flu

Our cut little and cuddly cats that purr at us and give us so much love seems be susceptible to catch the swine flu. In fact, a cat in Iowa has tested positive for the H1N1 virus, state officials confirmed this morning, "marking the first ...

November 19, 2009 | Embryonic Stem Cells May Be Used To Create New Skin

Boston (SmartAboutHealth) - A new study out of France has revealed that embryonic stem cells may be used to actually create new skin for humans.  The belief is that by using these embryonic stem cells to create new skin, that it could prove extremely helpful in the treatment of burn victims.  Burn victims usually have to wait for skin grafts when they suffer their injuries, but these can take quite some time to develop.  This i sbecause they come ...

November 18, 2009 | Back Pain Linked To Everyday Activites

While that occasional back pain may go away after some rest and pain medication, many back pain sufferers are not aware that everyday activities - from wearing high heels to long work hours - can repeatedly strain the spine may lead to more ...

Archive list: 1 2 3 4 5 6 7 8 [9] 10 11 12 13 14 15 16 17

Related articles:

Stoicism and emotional repression

  Society has different rules with regards to the way that men and women are supposed to express themselves. Men are generally regarded as the ones who are supposed to give comfort and strength. If they break down, cry, or seek comfort they may lose face. Women and other men do not give men an option to express feeling sad, tired, weak, depressed, inadequate, needy, or lonely without sacrificing their masculinity.  Men are also four times more likely to ...

Section: Mens health risks

Risk-taking - media encouragement

  According to Arran Stibbe, men's health problems and behaviors can be linked to the socialized gender role of men in our culture. In exploring magazines, he found that they promote traditional masculinity. The magazine celebrates "male" things such as liking guns, fast cars, and fast women and reading pornography regularly. In the magazine several "ideal" men are promoted. The problem: all these men have health risks.  The bodybuilder image that is promoted usually has poor exercise regimens that fail to work out the whole body or do ...

Section: Mens health risks

Treatment - surgery

  Surgical interventions are rarely used for IC/PBS. Surgical intervention is very unpredicatable for IC/PBS, and is considered a treatment of last resort when all other treatment modalities have failed and pain is severe. Some patients who opt for surgical intervention continue to ...

Section: Interstitial cystitis

News

December 20, 2009

Wii, Xbox 360 and Other Video Games Offer Some Benefits

Wii, Xbox 360, PlayStation, and other video games are hot on holiday gift lists, but some parents wonder whether these games offer any benefits or are detrimental to kids. The results of a new study may put some minds at ease, while others may not.  According to the ...

December 18, 2009

Should You Be Shoveling Snow?

Yes, the weather outside is frightful, and soon you will have to think about shoveling snow. But should you be the one doing the work? Who should and should not shovel snow, and how can you do it ...

December 17, 2009

Athletes who take NSAID's to prevent pain may be doing more harm than good

According to Stuart Warden, a researcher who studies musculoskeletal health and sports medicine, athletes who ritualistically take NSAID's to prevent post event and workout soreness and inflammation may be depriving the body of healing, ...

Blogroll