Sections

Alphabetical list:

A B C D E F G H I J K L M N O P R S T U V W X Y Q Z 1 2 3 4 5 6 7 8 9

News: November 23, 2009

Genetic Variant Slows AIDS Progression

November 23, 2009

Scientists report that a genetic variation appears to play a major role in slowing disease progression in HIV-infected patients.
In fact, those with the variation appear to take years longer to develop AIDS and die of complications of the disease.
"We're honing in on factors that vary across individuals that make a person more or less susceptible to HIV, in terms of how rapidly someone develops the disease," said study co-author Mary Carrington, a senior principal investigator at the U.S. National Cancer Institute.
However, this new knowledge won't translate into immediate benefits for patients with HIV.
AIDS remains a major killer in many parts of the world, but HIV - the virus that causes it - doesn't affect infected people the same way. "People progress to AIDS at hugely different rates," Carrington explained. "Some people progress within a year, while some have been infected for 20 years and still control the virus and don't have the disease."
It appears that three factors affect how the disease strikes a person, she said. One is the environment: the world in which a person lives. Another is the patient's genetic makeup. And the third is the genetic makeup of the virus itself.
In the study, published in the Nov. 22 online edition of Nature Genetics, Carrington and colleagues looked at genetic and medical records for hundreds of HIV-infected men. They were trying to see if genetic variations affected how the men fared.
The researchers found that a variation linked to higher levels of a protein known as HLA-C boosted the men's ability to avoid progressing to AIDS. It appeared to delay both the progression to AIDS and to death by years, Carrington said.
The genetic variation makes it easier for the immune system to kill cells that have been infected with the virus, she said. It does this by allowing immune cells to gain greater access to the infected cells, she explained.
Carrington said this genetic variation isn't related to another gene-related trait that makes some people virtually immune to HIV.
The study "hints at ways we might ultimately develop a vaccine or immune-based therapies that could modify or maybe even prevent the development of HIV disease," said Rowena Johnston, vice president of research with the Foundation for AIDS Research in New York City.
"The finding that a single piece of DNA can be strongly associated with something as complex as the control of HIV soon after infection is especially intriguing, not least because we know that early control of infection sets the stage for the entire course of the disease," Johnston noted.
What's next? The ultimate goal, Carrington said, is "to have a complete list of every genetic variance that is affecting how rapidly the disease develops."
That, in turn, could help physicians figure out how to better treat patients.


Archive issues: (50)

Archive list: 1 2 3 4 5 6 7 8 9 10 [11] 12 13 14 15 16 17

November 14, 2009 | Helping Children Cope With Stress

As adults we think of childhood as being happy and carefree, however today our world is different. What kinds of stress do children experience? Children in today's world have many concerns. Typical stresses would include school work and socialization however, the stress doesn't stop ...

November 13, 2009 | California H1N1 study shows high rates of death over age 50

An examination of H1N1 fatalities in California shows that after hospitalization, most deaths from swine flu occurred in those over age 50. The findings differ from reports that H1N1 flu primarily affects younger people and causes mild illness.  The study, appearing in the ...

November 12, 2009 | Increase in hot tub injuries raises concern for children

New findings show that over the past two decades, injuries from hot tubs have been increasing. A national study conducted by the Center for Injury Research and Policy of The Research Institute at Nationwide Children's Hospital found that hot tub injuries increased from 2,500 to more than 6,600 injuries per year between 1990 and 2007. Most injuries occur in those over age sixteen, but children are especially at risk for serious injury.  The study, ...

Archive list: 1 2 3 4 5 6 7 8 9 10 [11] 12 13 14 15 16 17

Related articles:

About mens health risks

  Mortality rates for all of the 15 leading causes of death for the total population are higher for males than females in America. Men die almost seven years earlier than women. Men are more likely to suffer from chronic illnesses, to suffer a traumatic brain injury, and to die from acquired immune deficiency syndrome ...

Section: Mens health risks

Vacuum Therapy

  These work by placing the penis in a vacuum cylinder device. The device helps draw blood into the penis by applying negative pressure. A tension ring is applied at the base of the penis to help maintain the erection. This type of device is sometimes referred to as penis pump and may be used just prior to sexual intercourse. Several ...

Section: Erectile Dysfunction

Chronic prostatitis/chronic pelvic pain syndrome - nomenclature

  The name of this disorder is evolving. In 2007, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) began using the umbrella term Urologic Chronic Pelvic Pain Syndromes (UCPPS), for research purposes, to refer to pain syndromes associated with the bladder (i.e. interstitial cystitis/painful bladder syndrome, IC/PBS) and the prostate gland (i.e. chronic prostatitis/chronic pelvic pain syndrome, CP/CPPS).    

Section: Prostatitis

News

December 20, 2009

Wii, Xbox 360 and Other Video Games Offer Some Benefits

Wii, Xbox 360, PlayStation, and other video games are hot on holiday gift lists, but some parents wonder whether these games offer any benefits or are detrimental to kids. The results of a new study may put some minds at ease, while others may not.  According to the findings reported in the latest ...

December 18, 2009

Should You Be Shoveling Snow?

Yes, the weather outside is frightful, and soon you will have to think about shoveling snow. But should you be the one doing the work? Who should and should not shovel snow, and how can you do it safely?  Every ...

December 17, 2009

Athletes who take NSAID's to prevent pain may be doing more harm than good

According to Stuart Warden, a researcher who studies musculoskeletal health and sports medicine, athletes who ritualistically take NSAID's to prevent post event and workout soreness and ...

Blogroll