Sections

Alphabetical list:

A B C D E F G H I J K L M N O P R S T U V W X Y Q Z 1 2 3 4 5 6 7 8 9

News: November 9, 2009

Two Antibiotics Linked to Birth Defects

November 9, 2009

Most antibiotics used during pregnancy are safe, but researchers have found a link between two commonly prescribed drugs and birth defects.

The study, part of the National Birth Defects Prevention Study and published in the November issue of Archives of Pediatrics and Adolescent Medicine, is the first analysis of antibiotic use in pregnancy. Researchers analyzed data from 13,155 mothers in 10 states whose infants had birth defects and compared them to mothers in the same region who had healthy babies.

It found that mothers of babies with birth defects were more likely to report taking two types of antibiotics used to treat urinary tract infections during the first three months of pregnancy - sulfa drugs such as Bactrim and Septra, and nitrofurantoins, a urinary germicide that includes the brand names Furadantin, Macrobid, and Macrodantin.

Penicillin, the most commonly prescribed antibiotic in early pregnancy, was found to be safe, but was linked to a slightly increased risk for limb defects. Also found to be safe were cephalosporins and quinolones.

Lead author of the study, Krista Crider, a geneticist with the Centers for Disease Control and Prevention said that this was the first study to find an association with the drugs and birth defects and additional studies are need to confirm the findings.

Sulfa drugs are the oldest antibiotics and some animal studies have found harm during pregnancy. The study found this group of drugs to be associated with six birth defects, more than any other class of antibiotic. Defects linked to sulfa drugs included rare brain and heart defects and shortened limbs. Anencephaly, a fatal brain and skull malformation linked to sulfa drugs, affects about 1 in 10,000 births in the United States per March of Dimes data.

Doctors have previously viewed nitrofurantoins as safe to treat urinary tract infections during pregnancy. The four defects most commonly linked with these medications included hypoplastic left heart syndrome, atrial septal defect, eye defects, and cleft lip and palate. Cleft palate occurs in about 20 births out of 10,000 and was twice as likely to occur with women who had taken the nitrofurantoins.

It is unclear whether the birth defects were caused by the drugs or by the infections being treated. Bacterial infections themselves can cause problems for the fetus if left untreated, including preterm birth, low birth weight and blindness, so pregnant women shouldn't avoid antibiotics entirely. Instead, women should discuss antibiotics choices with their doctors.

Additional Sources Include: The Centers for Disease Control and Prevention and the March of Dimes



Archive issues: (50)

Archive list: 1 2 [3] 4 5 6 7 8 9 10 11 12 13 14 15 16 17

December 08, 2009 | Tamiflu May Be Inneffective In Fighting Effects Of Flu

Washington (SmartAboutHealth) - According to a new review, the popular Tamiflu is weak when it comes to the effect it has in preventing effects of the flu, such as the development of pneumonia.  The ...

December 7, 2009 | Surprised? Black market steroids usually mislabeled

The risks of anabolic steroids - used by some athletes to build muscle mass - are by now well-documented. But it turns out, perhaps not surprisingly, that steroids bought illegally through "underground labs" and over the internet generally aren't what their labels say they are, researchers reported yesterday at the American Academy of Addiction Psychiatry's annual meeting in Los Angeles.  Steroid users often complain that the drugs they had bought ...

December 6, 2009 | Prostate Hormone Therapy May Up Heart Risks

Diabetes, heart attacks and other cardiovascular problems appear to be more common in men with prostate cancer who are treated with androgen deprivation therapy, which reduces or eliminates the male sex hormones that can promote cancer growth, a new study has found.  The finding indicates that androgen therapy is overused because its benefits have not ...

Archive list: 1 2 [3] 4 5 6 7 8 9 10 11 12 13 14 15 16 17

Related articles:

Alprostadil

  Alprostadil can be injected into the penis or inserted using a special applicator - usually just before sexual intercourse. Alprostadil has also become available in some countries as a topical cream (under the brand name Befar), and preliminary studies have shown a clinical efficacy of up to 83%. It has an onset of action of 10-15 minutes and its effects can last over 4 hours.    

Section: Erectile Dysfunction

Overview and symptoms

  Erectile dysfunction is characterized by the regular or repeated inability to obtain or maintain an erection. There are several ways that erectile dysfunction is analyzed:  Obtaining full erections at some times, such as when asleep (when the mind and psychological issues, if any, are less present), tends to suggest the physical structures are functionally working. However, the opposite case, a lack of nocturnal erections, does not imply ...

Section: Erectile Dysfunction

Independence and invulnerability

  Men are significantly less likely to visit their physicians to receive preventive health care examinations. Men make 134.5 million less physician visits than American women each year - making only 40.8% of all physician visits. A quarter of the men who are 45 to 60 do not have a personal physician. Men fail to make advised annual heart checkups. Men between 25 and 65 are four times more likely to die from cardiovascular disease than women.  Men are more likely to be diagnosed in a later stage of a terminal illness because ...

Section: Mens health risks

News

December 20, 2009

Wii, Xbox 360 and Other Video Games Offer Some Benefits

Wii, Xbox 360, PlayStation, and other video games are hot on holiday gift lists, but some parents wonder whether these games offer any benefits or are detrimental to kids. The results of a new study may put some minds at ease, while others may ...

December 18, 2009

Should You Be Shoveling Snow?

Yes, the weather outside is frightful, and soon you will have to think about shoveling snow. But should you be the one doing the work? Who should and should not shovel snow, and how can you do it safely?  Every winter, approximately 1,200 Americans die from a heart attack or another type of cardiac incident ...

December 17, 2009

Athletes who take NSAID's to prevent pain may be doing more harm than good

According to Stuart Warden, a researcher who studies musculoskeletal health and sports medicine, athletes who ritualistically take NSAID's to prevent post event and workout soreness and inflammation may be depriving the body of healing, in addition to risking other long term health problems. Taking anti inflammatory medications before running or other athletic ...

Blogroll